Science
Mechanism of Action
Functions as a comprehensive skin matrix protector by inhibiting collagenase and elastase enzymes that break down structural proteins, while concurrently stimulating new collagen and elastin synthesis in fibroblasts. The high concentration of polyphenols and flavonoids provides potent antioxidant protection against free radical damage, while anti-inflammatory compounds help strengthen barrier function through increased involucrin production.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 In vitro studies at 0.1% concentration demonstrated 62% collagenase inhibition at 100 μg/mL, outperforming standard reference compound 1,10-phenanthroline
- 02 56-day clinical trial showed 100% of participants experienced increased skin flexibility and hydration, with 90%+ reporting improved firmness and texture
- 03 Clinical study of 34 women aged 50-65 demonstrated significant reduction in crow's feet and fine lines with twice-daily application
Transparency
Dusting Analysis
Limited commercial availability and specialized extraction requirements make dusting unlikely; clinical efficacy observed at 0.1% concentration suggests meaningful inclusion levels in formulations
The Formula
Formulation
Stability
Water-soluble extract requiring cold-process addition to preserve polyphenol bioactivity; temperature-sensitive compounds degrade under heat exposure
Synergies
- Vitamin C
- Niacinamide
- Peptides
Conflicts
- Strong oxidizing agents
- High pH formulations above 6.0
Safety
Safety Profile
EU CosIng approved for skin conditioning applications; EWG low hazard rating (Score: 1) for cancer and developmental toxicity concerns
Your Skin
Skin Compatibility
Our Assessment
Verdict
A scientifically-backed botanical extract with proven multi-target anti-aging efficacy and excellent safety profile across all skin types.
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References
Sources