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ACANTHOPANAX SESSILIFLORUS STEM EXTRACT.

Valuable / SKIN CONDITIONING

A botanical extract derived from the stems of Acanthopanax sessiliflorus that delivers potent antioxidant protection while supporting skin's natural defense mechanisms. Clinical research demonstrates remarkable anti-aging properties through collagen preservation and enhanced cellular resistance to environmental stressors.

Antioxidant Skin conditioning Anti-inflammatory Photoprotective

Science

Functions as a dual-action antioxidant and anti-inflammatory agent that specifically targets matrix metalloproteinases (MMP-1 and MMP-3) to prevent collagen breakdown. Simultaneously modulates stress-responsive gene pathways to enhance cellular resilience against oxidative damage and UV-induced aging.


Research

Medium confidence
Effective range 0.01–0.1%
Optimal

0.05%

Key findings

  1. 01 C. elegans longevity studies at 0.01% showed 16.8% increase in lifespan with enhanced UV resistance
  2. 02 Antioxidant capacity testing at 0.1% demonstrated activity comparable to vitamin C in ABTS/DPPH assays

Transparency

Not commonly dusted
Min. effective
0.001%
Red flag below
0.0001%

Botanical extracts are rarely dusted due to extraction costs, but concentrations below 0.001% would provide minimal bioactive compound delivery


The Formula

Solubility
Water
Optimal pH 5 – 6
0 7 14

Stability

Maintains optimal bioactivity around pH 5.5 with excellent water miscibility due to aqueous-ethanol extraction method

Synergies

  • Vitamin C
  • Niacinamide
  • Peptides

Conflicts

  • Strong oxidizing agents
  • Highly alkaline ingredients (pH > 8.0)

Safety

CIR Status
Not reviewed by CIR
Sensitization risk Low

Listed in EU CosIng database as skin conditioning agent with no regulatory restrictions. Related Acanthopanax species show favorable safety profiles.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed botanical antioxidant with proven anti-aging mechanisms and universal skin compatibility.


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