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ACANTHOPANAX SESSILIFLORUS BARK/ROOT/STEM EXTRACT.

Valuable / SKIN CONDITIONING

A potent botanical extract derived from Korean five-leaf aralia that delivers antioxidant protection comparable to vitamin C while inhibiting collagen-degrading enzymes. This multifunctional ingredient demonstrates significant photoaging protection by suppressing UV-induced matrix metalloproteinases at concentrations as low as 0.01%.

antioxidant skin conditioning anti-inflammatory photoprotective anti-aging

Science

Functions through multiple pathways including ROS neutralization via phenolic compounds like syringaresinol and chlorogenic acid, downregulation of collagen-degrading enzymes (MMP-1, MMP-3, MMP-9), and suppression of inflammatory mediators (IL-6, TNF-α) through NF-κB pathway inhibition


Research

High confidence
Effective range 0.003125–1%
Optimal

0.1%

Key findings

  1. 01 0.1% concentration achieved vitamin C-equivalent antioxidant capacity in ABTS and DPPH assays
  2. 02 0.02% demonstrated 56% tyrosinase inhibition and 53% elastase inhibition
  3. 03 3.125-200 µg/ml range showed zero cytotoxicity while preventing UVB-induced MMP expression

Transparency

Not commonly dusted
Min. effective
0.001%
Red flag below
0.001%

Given proven efficacy at 0.003125% (3.125 µg/ml), concentrations below 0.001% would be considered insufficient for meaningful antioxidant or anti-aging benefits


The Formula

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Maximum phenolic stability achieved at neutral pH (~7.0), remains stable in mildly acidic conditions, phenolic actives degrade rapidly above pH 8.0

Synergies

  • vitamin C
  • niacinamide
  • peptides
  • other antioxidants

Conflicts

  • strong oxidizing agents
  • highly alkaline ingredients

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Approved as food ingredient in China (2008), listed in EU CosIng database, traditional use history supports safety profile


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Well-researched botanical antioxidant with proven efficacy at low concentrations and excellent safety profile across all skin types.


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