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Moumoujus

ACANTHOPANAX SENTICOSUS STEM EXTRACT.

Valuable CAS 84696-12-8 / SKIN CONDITIONING

A potent adaptogenic extract from Siberian ginseng stems that delivers robust anti-photoaging benefits through dual-action collagen protection and synthesis enhancement. Rich in eleutherosides and polysaccharides, this botanical powerhouse demonstrates clinically-verified abilities to combat UV-induced aging while strengthening skin barrier resilience across all skin types.

Summary

skin conditioning antioxidant anti-aging skin protecting

Science

Mechanism of Action

Functions as a skin adaptogen by delivering eleutherosides B and E alongside flavonoids and polysaccharides that neutralize free radicals and combat UV damage. Actively suppresses UVB-induced matrix metalloproteinase-1 (MMP-1) expression to prevent collagen breakdown while simultaneously stimulating type I procollagen synthesis. Additionally modulates inflammatory pathways to enhance barrier function and skin resilience under environmental stress.

Research

Clinical Evidence

High confidence
Effective range 0.0005–5%
Optimal

0.001%

Key findings

  1. 01 Demonstrated anti-wrinkle efficacy of 59% at 5 ppm and 78% at 10 ppm in collagen synthesis assays
  2. 02 Suppressed UVB-induced MMP-1 expression and increased Type I procollagen in human dermal fibroblasts

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.01%
Red flag below
0.005%

Given the demonstrated efficacy at extremely low concentrations (5-10 ppm), any presence above 0.01% suggests genuine formulation intent rather than dusting for marketing purposes.

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

Exhibits maximum stability in weakly acidic conditions around pH 4.0-4.5. Alkaline environments above pH 7.0 trigger oxidative polymerization of polyphenolic compounds, causing formula discoloration and activity loss.

Synergies

  • vitamin C
  • niacinamide
  • peptides
  • hyaluronic acid

Conflicts

  • strong oxidizing agents
  • highly alkaline ingredients

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

While the stem extract specifically lacks CIR review, related Acanthopanax extracts demonstrate excellent safety profiles in clinical assessments. Recommended usage between 0.1-5% in finished formulations based on dietary study safety data.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A scientifically-backed adaptogenic extract that delivers measurable anti-aging benefits at remarkably low concentrations, making it a cost-effective addition to premium skincare formulations.

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