Science
Mechanism of Action
Functions through dual pathways: stimulates keratinocyte proliferation via ERK-mediated mTOR signaling for enhanced skin regeneration, while inhibiting inflammatory mediators including nitric oxide and iNOS. Additionally forms film-forming polysaccharide layers that deliver immediate physical skin-tightening and barrier enhancement.
Research
Clinical Evidence
Medium confidence0.08%
Key findings
- 01 Demonstrated keratinocyte proliferation enhancement through mTOR pathway activation
- 02 Inhibited monocytic adhesion to endothelial cells with suppression of LFA-1 and Mac-1 inflammatory markers
- 03 European Pharmacopoeia standardized extracts at 0.08% eleutherosides B and E showed significant calming effects
Transparency
Dusting Analysis
Limited commercial penetration and specialized extraction requirements make dusting unlikely for this botanical extract
The Formula
Formulation
Stability
Polysaccharide components achieve optimal stability at pH 6.0, while polyphenolic actives prefer pH 4.3. Maintains thermal stability up to 50°C with degradation risk at elevated temperatures.
Safety
Safety Profile
Distinguished from CIR-approved Panax Ginseng as different botanical genus. Listed in EU CoSING database as approved skin conditioning agent.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Well-researched adaptogenic extract offering dual anti-inflammatory and regenerative benefits with excellent skin tolerance across all types.
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References
Sources