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ACANTHOPANAX SENTICOSUS ROOT.

Valuable CAS 84696-12-8 / HUMECTANT

A botanical adaptogen derived from Siberian ginseng root that strengthens skin's resilience against environmental stressors through active compounds called eleutherosides. Its polysaccharide components provide dual-action benefits by delivering antioxidant protection while creating a moisture-retaining film on the skin surface.

skin conditioning skin protecting soothing astringent

Science

Functions as a topical adaptogen by enhancing skin's natural defense mechanisms through eleutherosides B and E, which boost antioxidant enzyme activity (SOD, CAT) and suppress inflammatory cytokines IL-1β and TNF-α. The polysaccharide fraction forms a protective film layer that improves moisture retention while providing immediate skin-smoothing effects through structural tightening upon application.


Research

High confidence
Effective range 0.08–0.8%
Optimal

0.08%

Key findings

  1. 01 European Pharmacopoeia standardization shows 0.08% concentration ensures adaptogenic efficacy when eleutherosides B and E are properly standardized
  2. 02 2024 study demonstrated polysaccharide CQ-1 at 0.4-0.8 mg/mL significantly increased antioxidant enzyme activity and reduced cellular damage markers

Transparency

Not commonly dusted

Well-established adaptogenic ingredient with standardized extraction methods and documented efficacy thresholds, making dusting less common in professional formulations


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Demonstrates excellent stability in aqueous systems with optimal extraction efficiency at pH 4.3. Polysaccharide components may undergo beneficial structural changes during processing that enhance skin-tightening properties.

Conflicts

  • strong oxidizing agents
  • prolonged high-temperature exposure above 80°C

Safety

CIR Status
Safe as used
Sensitization risk Low

CIR Panel assessment confirms safety in current cosmetic applications. Unlike Panax ginseng, this species lacks ginsenosides and therefore avoids phytoestrogen-related concerns.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed adaptogenic ingredient that delivers measurable stress-protection and antioxidant benefits with excellent safety across all skin types.


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References