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6-TERT-BUTYLQUINOLINE.

Optional CAS 65442-31-1 / PERFUMING

A heterocyclic aromatic compound primarily utilized as a fragrance component in cosmetic formulations, delivering distinctive woody, leather, and vetiver-like olfactory notes. Its lipophilic structure allows it to function as a solubility enhancer for other hydrophobic ingredients while contributing to the sensory profile of skincare products.

perfuming

Science

Functions primarily through olfactory interaction rather than direct skin biochemistry, providing fragrance enhancement while potentially improving the solubilization of lipophilic actives due to its hydrophobic tert-butyl substituent and aromatic quinoline backbone.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

As a specialized fragrance ingredient with limited cosmetic applications, this compound is rarely subject to marketing dusting practices


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Demonstrates excellent chemical stability as a nitrogen-containing heterocycle with minimal water solubility (17.97 mg/L) but high alcohol and organic solvent compatibility (logP ~3.9)


Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

IFRA guidelines recommend maximum 1.0% concentration in fragrance concentrates; classified as Category 2 skin and eye irritant at full strength according to GHS standards


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A specialized fragrance ingredient with moderate irritancy concerns that serves primarily aesthetic rather than therapeutic functions in precision skincare.


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