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6-AMINO-O-CRESOL.

Avoid CAS 17672-22-9 / HAIR DYEING

A synthetic aromatic amine compound primarily developed as a precursor molecule for oxidative hair dyeing systems. This ingredient works by diffusing into hair structures where it undergoes oxidation to create permanent color molecules, though it has no established benefits for skincare applications.

Hair colorant

Science

Functions exclusively as a hair dye precursor through oxidative coupling reactions with hydrogen peroxide, forming large chromophoric molecules that become trapped within hair fibers to create permanent coloration


Research

Low confidence
Effective range ≤0.7%
Optimal

N/A


Transparency

Not commonly dusted

This ingredient has no established skincare benefits and is primarily used in hair coloring, making dusting analysis irrelevant for precision skincare formulations


The Formula

Solubility
Water
Optimal pH 1.9 – 2.1
0 7 14

Stability

Demonstrates excellent long-term stability exceeding 8 years when stored in dry, light-protected conditions, though pH-dependent solubility requires careful formulation consideration

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Insufficient data
Max tested
0.7%
Pregnancy
Caution
Sensitization risk High

CIR Panel reopened safety assessment in 2022 following EU prohibition, currently classified as insufficient data for safety determination with known skin and eye irritant properties


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

This hair dye precursor offers no skincare benefits and carries significant safety concerns including EU prohibition and CIR insufficient data status.


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