Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

5-PHENYLHEX-3-EN-2-ONE.

Optional CAS 60405-50-7 / PERFUMING

A synthetic aromatic ketone compound primarily utilized as a fragrance component in cosmetic formulations. This alpha,beta-unsaturated ketone provides specific olfactory profiles while demonstrating acceptable safety margins at regulated concentrations, though it offers no documented skin-improvement benefits.

fragrance

Science

Functions exclusively as an olfactory agent, providing fragrance to cosmetic products through volatile aromatic properties. The compound undergoes potential metabolic oxidation upon skin contact but does not deliver physiological benefits such as anti-aging or hydration enhancement.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 3D skin COMET assay at 35 µg/cm² showed no genotoxic response in reconstructed human skin models
  2. 02 In vitro micronucleus testing at 25 µg/ml demonstrated clastogenic potential in isolated lymphocytes but negative results in 3D skin models

Transparency

Not commonly dusted

As a fragrance-only ingredient with strict concentration limits (0.0064%), dusting is not applicable since it provides no functional skincare benefits to amplify through higher concentrations


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Requires protection from extreme heat and oxidizing conditions due to its enone structure susceptibility to Michael addition reactions

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Nucleophilic amino-containing ingredients

Safety

CIR Status
Not reviewed
Max tested
0.0064%%
Sensitization risk Unknown

RIFM Expert Panel deemed safe as used via Threshold of Toxicological Concern approach. Conservative Dermal Sensitization Threshold of 64 µg/cm² applied due to limited sensitization data.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

A regulated fragrance component that serves purely aesthetic purposes with no skincare benefits, suitable only when specific scent profiles are desired.


Related

Finding similar ingredients…