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Moumoujus

5-METHOXY-M-CRESOL.

Valuable CAS 3209-13-0 / PERFUMING

A potent antimicrobial preservative that maintains formulation integrity by disrupting microbial cell membranes and preventing bacterial contamination. This phenolic compound functions as both a biocide and secondary fragrance component, offering dual functionality in skincare formulations.

Summary

preservative perfuming

Science

Mechanism of Action

Disrupts microbial cell membranes and induces protein unfolding in harmful microorganisms, creating an inhospitable environment for bacterial growth while maintaining formulation stability

Research

Clinical Evidence

High confidence
Effective range 0.15–0.35%
Optimal

0.15%

Key findings

  1. 01 Maintained therapeutic formulation stability for 39 months at 0.15% concentration without protein aggregation (ResearchGate/NIH PMC, 2025)

Transparency

Dusting Analysis

Not commonly dusted

Preservatives are typically used at effective concentrations rather than being dusted due to their critical antimicrobial function

The Formula

Formulation

Solubility
Both
Optimal pH 4.5 – 6.5
0 7 14

Stability

Demonstrates high stability but requires protection from air and light exposure to prevent oxidation and discoloration

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Aluminum
  • Aluminum alloys

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.5%
Sensitization risk Moderate

CIR Expert Panel classified as safe up to 0.5% concentration; higher levels may cause skin and eye irritation or burns

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Verdict

Valuable

An effective preservative system component that provides reliable antimicrobial protection when used within safe concentration limits.

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