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5-ISOPROPYL-2-METHYLANISOLE.

Optional CAS 6379-73-3 / PERFUMING

A monoterpenoid ether compound derived from thyme essential oil, primarily functioning as a fragrance component with secondary antimicrobial properties. This ingredient disrupts bacterial cell membranes while providing antioxidant protection against reactive oxygen species in cosmetic formulations.

fragrance masking antimicrobial

Science

Functions by compromising bacterial cell membrane integrity, causing intracellular leakage and bacterial death, while simultaneously neutralizing free radicals and preventing lipid peroxidation through its monoterpenoid structure


Research

Medium confidence
Effective range 0.02–3%
Optimal

1.5%

Key findings

  1. 01 Demonstrated potent antibacterial efficacy against pathogenic bacteria in controlled laboratory conditions

Transparency

Not commonly dusted

Primarily used as fragrance component rather than active ingredient, making dusting practices uncommon in skincare applications


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Maintains stability under standard storage conditions with flash point at 74-75°C; requires protection from light and heat exposure

Conflicts

  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Moderate

Classified as potential skin sensitizer and eye irritant in concentrated form; RIFM/IFRA guidelines establish 3% maximum in fragrance concentrates


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A specialized fragrance ingredient with modest antimicrobial benefits, suitable for non-sensitive skin types but limited by sensitization potential.


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