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Moumoujus

5-ETHYL-4-HYDROXY-2-METHYLFURAN-3(2H)-ONE.

Valuable CAS 27538-09-6 / PERFUMING

A heterocyclic aromatic compound that functions primarily as a perfuming agent while delivering secondary antioxidant and skin-brightening benefits. Originally developed for fragrance applications, this furan derivative demonstrates dual-action melanogenesis inhibition through both gene expression modulation and enzyme activity suppression.

Summary

perfuming antioxidant skin brightening

Science

Mechanism of Action

Functions as a reductone antioxidant that neutralizes free radicals and protects cellular membranes from oxidative stress. Simultaneously inhibits melanin production through a dual pathway: downregulating tyrosinase mRNA and protein expression at the genetic level while competitively inhibiting existing tyrosinase enzyme activity to prevent melanin formation.

Research

Clinical Evidence

Medium confidence
Effective range ≤1%
Optimal

N/A

Key findings

  1. 01 Dual-mechanism tyrosinase inhibition for skin depigmentation
  2. 02 Potent antioxidant protection against iron-induced erythrocyte membrane damage

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as a functional perfuming agent with established maximum concentration limits, making dusting practices less common

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Highly oxygen and heat sensitive, prone to decomposition into acetic and propionic acids. Requires storage at 2-8°C in airtight, light-protected containers.

Synergies

  • ascorbic acid
  • other antioxidants

Conflicts

  • strong oxidizing agents
  • high temperatures above 200°F
  • prolonged oxygen exposure

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

FEMA GRAS status for food applications and follows IFRA fragrance guidelines. GHS classifies pure form as skin and eye irritant, but demonstrates low irritancy at typical use concentrations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A multifunctional ingredient that effectively combines fragrance enhancement with scientifically-supported antioxidant and depigmenting properties, though formulation stability requires careful consideration.

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