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Moumoujus

5-BROMO-5-NITRO-1,3-DIOXANE.

Optional CAS 30007-47-7 / PRESERVATIVE

A water-soluble antimicrobial preservative that protects rinse-off formulations from bacterial and fungal contamination through targeted protein oxidation. This crystalline compound functions as both a broad-spectrum biocide and formaldehyde releaser, though its use is strictly limited to wash-off products due to regulatory restrictions.

Summary

preservative antimicrobial agent

Science

Mechanism of Action

Operates by oxidizing essential protein thiol groups within microbial cells, disrupting critical enzyme activity and cellular metabolism to prevent growth of both gram-positive and gram-negative bacteria as well as fungi

Research

Clinical Evidence

Medium confidence
Effective range 0.1–0.1%
Optimal

0.1%

Key findings

  1. 01 Demonstrated safety profile in rinse-off cosmetic applications when formulated without amine or amide compounds

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.15%

Regulatory maximum of 0.1% creates clear upper limit with minimal room for cosmetic dusting practices

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Maintains stability across pH 5.0-8.0 range with 2+ year shelf life when stored as dry crystalline solid; degrades rapidly under alkaline conditions with accelerated formaldehyde release

Conflicts

  • Secondary amines
  • Amides
  • Strong oxidizing agents
  • High pH formulations

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.1%
Pregnancy
Caution
Sensitization risk Moderate

Restricted exclusively to rinse-off products; prohibited in leave-on formulations in EU and Canada; banned entirely in Japanese cosmetics; incompatible with amine-containing ingredients due to nitrosamine formation risk

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Verdict

Optional

A functional but highly restricted preservative limited to rinse-off applications with significant regulatory constraints and formulation incompatibilities.

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