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5-AMINO-4-FLUORO-2-METHYLPHENOL SULFATE.

Avoid CAS 163183-01-5 / HAIR DYEING

A specialized oxidative coupler compound primarily used in professional hair coloring formulations. This fluorinated phenol derivative functions by coupling with oxidizing agents to create permanent color molecules within the hair shaft. While technically approved for hair applications at concentrations up to 1.1%, it has no established role in skincare formulations.

Hair dyeing

Science

Functions as a coupling agent in oxidative hair dye systems, reacting with hydrogen peroxide and primary intermediates to form large chromophore molecules that become trapped within keratin fibers for permanent coloration.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

This ingredient is specific to hair coloring applications and would not be used in skincare formulations for dusting purposes.


The Formula

Solubility
Water
Optimal pH 6.5 – 11.5
0 7 14

Stability

Requires alkaline conditions for optimal performance; susceptible to premature oxidation when exposed to air or oxidizing agents before intended use

Conflicts

  • Strong oxidizing agents (premature activation)
  • Strong acids (sulfate salt destabilization)

Safety

CIR Status
Not reviewed
Max tested
1.1%
Sensitization risk Moderate

EU-regulated under Annex III/250 with mandatory allergen warnings; concentration limit applies to final hair application after mixing with oxidants


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

A hair-specific ingredient with no skincare benefits and moderate sensitization potential that should be avoided in facial formulations.


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