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4-METHYLQUINOLINE.

Avoid CAS 491-35-0 / PERFUMING

A heterocyclic aromatic compound primarily employed as a fragrance ingredient in cosmetic formulations. Also known as lepidine, this synthetic molecule serves as a perfuming agent rather than an active skincare ingredient. Its presence on California's Proposition 65 list raises significant safety concerns for topical applications.

perfuming

Science

Functions solely as a fragrance component without any established biological activity on skin cells or tissues. Does not interact with skin receptors or cellular processes for therapeutic benefit.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted
Red flag below
0.6%

Not typically used for ingredient dusting due to its classification as an irritant and potential carcinogenicity concerns


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Requires careful handling due to light and air sensitivity; volatile in steam conditions and must be stored under inert atmosphere in dark conditions

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Not reviewed
Max tested
0.6%
Pregnancy
Caution
Sensitization risk High

Classified as irritant (R36/37/38) with documented mutagenicity and carcinogenicity in animal studies showing liver and skin tumor development in mice


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

The significant safety concerns including potential carcinogenicity and irritation risk outweigh any fragrance benefits for precision skincare formulations.


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