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4-METHYL-4-PHENYL-2-PENTANONE.

Optional CAS 7403-42-1 / PERFUMING

A synthetic aromatic compound primarily valued for its distinctive woody, vetiver-like fragrance profile in cosmetic formulations. While traditionally employed as a perfuming agent, emerging patent research suggests potential auxiliary benefits in supporting skin turnover and enhancing active ingredient penetration in anti-aging applications.

Perfuming Penetration enhancer Texture modifier

Science

Functions predominantly as an olfactory enhancer, providing rooty, woody aromatic notes with gardenia undertones. In specialized anti-aging formulations, may serve as a penetration enhancer and texture modifier, potentially supporting the delivery and spreadability of primary active ingredients while contributing to improved skin radiance.


Research

Medium confidence
Effective range 0.01–8%
Optimal

1%

Key findings

  1. 01 RIFM safety assessment confirming non-sensitizing and non-phototoxic properties at concentrations up to 8.0%
  2. 02 Patent literature suggesting skin turnover benefits when used at 0.01-1.0% in anti-aging compositions alongside vitamin C derivatives

Transparency

Not commonly dusted

Insufficient market penetration data available for dusting analysis assessment


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Demonstrates excellent stability across diverse formulation types including lotions, soaps, and powder systems, but exhibits degradation when exposed to bleaching compounds

Synergies

  • Vitamin C derivatives
  • Anti-aging actives

Conflicts

  • Bleaching agents
  • Strong oxidizing compounds

Safety

CIR Status
Not reviewed
Max tested
8%
Sensitization risk Low

RIFM/IFRA evaluation confirms safety profile with margin of exposure exceeding 100 for systemic toxicity. GHS classification indicates potential irritation in concentrated forms, but well-tolerated at typical use levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient with emerging potential as a formulation enhancer, though primarily valued for sensory rather than therapeutic benefits.


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