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4-METHYL-2-PHENYL-2-PENTENAL.

Optional CAS 26643-91-4 / PERFUMING

Also known as Cocoa Pentenal, this synthetic fragrance molecule delivers a distinctive cocoa-like, honey-sweet aroma to cosmetic formulations. While primarily serving sensory functions, emerging research suggests potential TRPA1 receptor modulation that may provide cooling effects in topical applications.

Perfuming Fragrance masking Sensory enhancement

Science

Functions primarily through olfactory receptor stimulation to provide characteristic fragrance benefits, with potential skin-level TRPA1 receptor inhibition that may contribute to sensory cooling effects and reduced irritation in certain formulations.


Research

Low confidence
Effective range 0.1–1%
Optimal

0.5%


Transparency

Not commonly dusted

As a fragrance ingredient with no established therapeutic benefits, this compound is not typically subject to dusting practices in skincare marketing.


The Formula

Solubility
Oil
Optimal pH 6.5 – 8
0 7 14

Stability

Alpha,beta-unsaturated aldehyde structure makes it highly susceptible to oxidative degradation and requires antioxidant stabilization such as alpha-tocopherol. Air-sensitive and must be stored under inert atmosphere.

Synergies

  • Alpha-tocopherol
  • Other antioxidant stabilizers

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Strong acids

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

EFSA has raised genotoxicity concerns for food applications, leading to EU food prohibition by February 2025. IFRA guidelines recommend concentrations below 0.5% for leave-on skin products. GHS classification includes skin and eye irritation warnings (H315, H319).


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A specialized fragrance ingredient with limited therapeutic value, best reserved for products where cocoa-scented sensory experience is desired at concentrations below 0.5%.


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