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4-METHYL-1-OXASPIROUNDECENE.

Optional CAS 68228-06-8 / PERFUMING

A synthetic fragrance molecule that delivers herbal, woody, and camphor-like scent notes while serving as an odor masker in skincare formulations. This oxaspirane compound functions purely as a sensory enhancer without therapeutic skin benefits, making it suitable for products where olfactory experience is prioritized.

perfuming odor masking

Science

Functions exclusively as a perfuming agent and odor neutralizer, providing sensory enhancement through its distinctive aromatic profile without direct skin-active mechanisms


Research

Medium confidence
Effective range ≤2.7%
Optimal

0.75%

Key findings

  1. 01 HRIPT testing at 0.75% concentration demonstrated non-sensitizing and non-irritating properties in human subjects

Transparency

Not commonly dusted

As a fragrance component without therapeutic claims, dusting is not typically relevant for this ingredient


The Formula

Solubility
Oil
Optimal pH 4.5 – 9.5
0 7 14

Stability

Demonstrates good stability across standard cosmetic pH ranges and benefits from encapsulation in surfactant-rich systems to prevent leakage

Conflicts

  • strong oxidizing agents
  • strong acids (risk of ring-opening or structural isomerization)

Safety

CIR Status
Not reviewed
Max tested
2.7%
Sensitization risk Low

RIFM safety assessment indicates 1.5% maximum for direct skin contact products, with potential pure form irritation according to ECHA data


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient that enhances product sensory experience without skin benefits, suitable for non-sensitive skin types seeking olfactory enhancement.


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