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Moumoujus

4-FLUORO-6-METHYL-M-PHENYLENEDIAMINE SULFATE.

Questionable CAS 173994-76-8 / 217311-43-8 / HAIR DYEING

A fluorinated phenylenediamine derivative primarily utilized as an oxidative hair dye precursor in professional coloring systems. This specialized coupler undergoes controlled oxidation to create stable chromophore molecules that permanently bond within hair fiber structures. While effective for its intended application, this ingredient carries notable sensitization potential and requires careful handling protocols.

Summary

hair dyeing oxidative coupling

Science

Mechanism of Action

Functions as a reactive intermediate that couples with oxidizing agents like hydrogen peroxide to generate large molecular weight pigment complexes that become mechanically trapped within hair cortex layers

Research

Clinical Evidence

Medium confidence
Effective range 0.1–10%
Optimal

5%

Key findings

  1. 01 General phenylenediamine class demonstrates effective dyeing properties but significant sensitization rates in exposed populations

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
1%

Given the sensitization potential and specialized hair dye application, concentrations above 0.5% in non-hair products would be concerning for unnecessary exposure risk

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 12
0 7 14

Stability

Sulfate salt provides enhanced stability versus free base form, though remains photosensitive and heat-labile with tendency toward oxidative degradation

Synergies

  • hydrogen peroxide
  • alkaline activators

Conflicts

  • metal chelators
  • strong acids
  • reducing agents

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
10%
Pregnancy
Caution
Sensitization risk High

CIR approval limited to hair dye applications up to 10% calculated as free base equivalent; known contact allergen requiring patch testing protocols

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Effective for specialized hair coloring applications but carries significant sensitization risks that limit broader cosmetic utility.

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