Science
Mechanism of Action
Inhibits the production of inflammatory mediators including prostaglandin E2, interleukin-6, and interleukin-8 that are induced by ultraviolet radiation, thereby reducing inflammatory responses that lead to redness and skin irritation
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 Significant reduction in facial erythema and improvement in uneven skin tone in mild to moderate rosacea patients over 4 weeks
Transparency
Dusting Analysis
Clinical efficacy established at 1% concentration with no evidence of effective lower concentrations
The Formula
Formulation
Stability
Requires protection from air and light exposure; should be stored under inert atmosphere; insoluble in water-based systems
Conflicts
- Strong oxidizing agents
- Strong bases
Safety
Safety Profile
FDA GRAS status for flavoring applications; potential irritation at concentrations above clinical standard
Your Skin
Skin Compatibility
Our Assessment
Verdict
A clinically validated anti-inflammatory ingredient with proven efficacy for redness reduction, though limited to oil-based formulations and requires careful handling.
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References
Sources