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4-ETHOXYBENZALDEHYDE.

Valuable CAS 10031-82-0 / FRAGRANCE, PERFUMING

A targeted anti-inflammatory compound that demonstrates clinically proven efficacy in reducing facial redness and improving uneven skin tone. This oil-soluble ingredient works by interrupting inflammatory cascades triggered by UV exposure, making it particularly effective for rosacea management and general redness reduction.

anti-inflammatory soothing perfuming

Science

Inhibits the production of inflammatory mediators including prostaglandin E2, interleukin-6, and interleukin-8 that are induced by ultraviolet radiation, thereby reducing inflammatory responses that lead to redness and skin irritation


Research

Medium confidence
Effective range 1–1%
Optimal

1%

Key findings

  1. 01 Significant reduction in facial erythema and improvement in uneven skin tone in mild to moderate rosacea patients over 4 weeks

Transparency

Not commonly dusted

Clinical efficacy established at 1% concentration with no evidence of effective lower concentrations


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Requires protection from air and light exposure; should be stored under inert atmosphere; insoluble in water-based systems

Conflicts

  • Strong oxidizing agents
  • Strong bases

Safety

CIR Status
Not reviewed
Max tested
1%%
Sensitization risk Low

FDA GRAS status for flavoring applications; potential irritation at concentrations above clinical standard


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

A clinically validated anti-inflammatory ingredient with proven efficacy for redness reduction, though limited to oil-based formulations and requires careful handling.


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