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Moumoujus

4-ETHOXY-M-PHENYLENEDIAMINE SULFATE.

Avoid CAS 6219-69-8 / 68015-98-5 / HAIR DYEING

4-Ethoxy-m-phenylenediamine Sulfate is a synthetic aromatic amine compound historically used as a coupling agent in permanent hair dye formulations. This ingredient has been prohibited in the European Union and numerous other jurisdictions due to significant safety concerns, including potential carcinogenicity from its metabolite 2,4-diaminoanisole.

Summary

hair dyeing

Science

Mechanism of Action

Acts as a precursor molecule that penetrates hair cuticles and undergoes oxidation-coupling reactions with primary intermediates to form stable pigment complexes within the hair shaft

Research

Clinical Evidence

High confidence
Effective range ≤3%
Optimal

N/A

Key findings

  1. 01 Demonstrated significant skin sensitization potential and contact dermatitis risk in patch testing studies

Transparency

Dusting Analysis

Not commonly dusted
Red flag below
0.1%

This ingredient is banned in many jurisdictions and should trigger immediate safety concerns at any concentration

The Formula

Formulation

Solubility
Water
Optimal pH 6.5 – 9.5
0 7 14

Stability

Extremely unstable in aqueous solutions, rapidly oxidizes causing brown/black discoloration unless protected with antioxidants like Erythorbic Acid or Sodium Metabisulfite

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Metallic salts

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
0%
Pregnancy
Caution
Sensitization risk High

Prohibited in EU under Annex II/406 due to carcinogenic concerns from its metabolite 2,4-diaminoanisole

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

This banned ingredient poses serious safety risks and should never be used in modern cosmetic formulations.

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