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4,6-DIMETHYL-PYRAN-2-ONE.

Optional CAS 675-09-2 / PERFUMING

A crystalline pyrone derivative primarily utilized as a fragrance component in cosmetic formulations, delivering distinctive sweet and caramel notes. While its 2-pyrone structure suggests potential antimicrobial properties, its main application remains as a perfuming agent in concentrations up to 1.0%.

perfuming

Science

Functions predominantly as a fragrance molecule, with its pyrone core structure potentially offering mild antimicrobial and anti-inflammatory activity, though these secondary benefits are not the primary focus in cosmetic applications.


Research

Medium confidence
Effective range 0.2–1%
Optimal

0.6%

Key findings

  1. 01 Demonstrated non-sensitizing properties when used as fragrance component in topical applications

Transparency

Not commonly dusted

Not typically used for dusting purposes; primarily incorporated for fragrance enhancement rather than functional skincare benefits


The Formula

Solubility
Both
Optimal pH 7 – 12
0 7 14

Stability

Maintains excellent stability as crystalline solid with notable water solubility (242 g/L at 60°C) and compatibility with organic solvents; requires storage at 2-8°C for long-term stability

Conflicts

  • Strong oxidizing agents
  • Strong alkaline compounds

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

RIFM assessment confirms no sensitization concerns at standard usage levels; systemic exposure (0.83 μg/kg/day) remains well below safety thresholds


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A safe, low-irritancy fragrance ingredient suitable for most skin types but offers limited functional skincare benefits beyond sensory enhancement.


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