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4,5-DIAMINO-1-((4-CHLOROPHENYL)METHYL)-1H-PYRAZOLE-SULFATE.

Avoid CAS 163183-00-4 / HAIR DYEING

A chlorinated pyrazole derivative primarily utilized as an oxidative hair dye precursor in permanent coloring systems. This compound requires alkaline conditions (pH 9-11) and oxidizing agents to function effectively, making it incompatible with typical skincare formulations. While occasionally listed in ingredient databases, it lacks established skin benefits and poses moderate sensitization risk.

hair dyeing

Science

Functions through oxidative coupling reactions where amino groups are oxidized to reactive intermediates that bind with coupler molecules to create permanent color pigments within hair structures


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Not applicable for skincare formulations as this ingredient serves no established cosmetic function for skin treatment


The Formula

Solubility
Water
Optimal pH 9 – 11
0 7 14

Stability

Requires highly alkaline environment for activation; degrades in skin-compatible acidic pH ranges (4.5-5.5)

Conflicts

  • Strong reducing agents
  • Acidic environments
  • Metallic salts

Safety

CIR Status
Safe as used
Max tested
3%
Sensitization risk Moderate

Regulatory approval limited to hair dye applications at maximum 3% concentration; classified as potential skin sensitizer


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

This hair dye ingredient has no established skincare benefits and requires incompatible formulation conditions.


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