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4,4'-DIAMINODIPHENYLAMINE SULFATE.

Avoid CAS 6369-04-6 / HAIR DYEING

A specialized oxidative hair dye precursor that creates permanent color through molecular polymerization within the hair shaft. This ingredient is specifically designed for professional hair coloring formulations where it contributes to the formation of blue-black to dark shades.

Hair dyeing Color formation Oxidative coupling

Science

Functions as a small molecule that penetrates the hair cuticle and undergoes oxidative coupling in the presence of hydrogen peroxide, forming larger colored pigment molecules that become trapped within the hair structure


Research

High confidence
Effective range 0.1–2%
Optimal

2%

Key findings

  1. 01 Demonstrated safe and effective performance as primary intermediate in oxidative hair dye systems with acceptable safety profile excluding sensitization potential

Transparency

Not commonly dusted

Not applicable for skincare formulations as this ingredient is exclusively restricted to hair coloring applications


The Formula

Solubility
Water
Optimal pH 7 – 8.2
0 7 14

Stability

Requires careful handling due to hygroscopic nature and photodegradation sensitivity. Most stable in acidic storage conditions but needs alkaline environment for activation.

Synergies

  • Hydrogen peroxide (oxidizing agent)
  • Alkaline activators

Conflicts

  • Strong acids
  • N-nitroso compounds
  • Moisture exposure
  • UV light

Safety

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk High

Approved exclusively for oxidative hair dye applications. Prohibited in eye area cosmetics due to blindness risk. Lacks FDA approval as color additive for non-hair products.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

Not suitable for precision skincare applications due to exclusive hair dye designation and significant sensitization potential.


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