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Moumoujus

3-NITRO-P-HYDROXYETHYLAMINOPHENOL.

Questionable CAS 65235-31-6 / HAIR DYEING

A specialized nitro dye compound primarily developed for hair coloring applications, functioning through physical adsorption rather than chemical bonding. This low molecular weight ingredient penetrates hair shafts effectively but has limited skincare applications due to its specific formulation requirements and sensitization profile.

Summary

hair dyeing colorant

Science

Mechanism of Action

Operates as a direct dye by diffusing into hair structures through its small molecular size, adhering via physical adsorption to keratin surfaces without forming chemical bonds with the substrate

Research

Clinical Evidence

High confidence
Effective range 1.85–6%
Optimal

3%

Key findings

  1. 01 SCCS evaluation at 3.0% in oxidative formulations showed safety profile
  2. 02 Non-irritating response demonstrated at 6.0% concentration in rabbit studies
  3. 03 Semi-permanent applications validated safe at 1.85% concentration

Transparency

Dusting Analysis

Not commonly dusted

Primarily used in hair care formulations with established concentration limits; not commonly found in skincare products

The Formula

Formulation

Solubility
Water
Optimal pH 7.4 – 9.5
0 7 14

Stability

Limited stability window of 4-6 hours at ambient temperature, extending to 9 days under refrigeration with light protection and inert atmosphere

Conflicts

  • strong oxidizing agents
  • light exposure
  • extended air contact

Safety

Safety Profile

CIR Status
Safe as used
Max tested
3%
Sensitization risk High

Classified as extreme sensitizer in LLNA testing; maximum 3.0% for oxidative applications, 1.85% for non-oxidative use

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Limited to hair applications with high sensitization risk, making it unsuitable for precision skincare formulations.

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