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3-NITRO-4-AMINOPHENOXYETHANOL.

Questionable CAS 50982-74-6 / HAIR DYEING

A substituted aromatic amine compound primarily developed as a direct hair colorant rather than a skincare active. This low molecular weight molecule can penetrate biological tissues but shows limited skin absorption (0.42%) and poses potential sensitization risks through protein complex formation.

Colorant

Science

Functions as a non-oxidative colorant that penetrates cellular structures through its small molecular size, bypassing the need for chemical activation. On skin contact, it may act as a hapten, forming complexes with skin proteins that could trigger delayed-type hypersensitivity reactions in predisposed individuals.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Not a skincare ingredient subject to dusting practices; primarily used in hair coloring applications with established concentration limits


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Maintains stability in aqueous systems for 9 days at 4°C under light protection and inert atmosphere conditions

Conflicts

  • Light exposure
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
0.15%
Sensitization risk Moderate

CIR approval limited to hair dye applications at 0.15% maximum. Demonstrates low dermal penetration but potential for contact sensitization exists.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Questionable

A hair dye ingredient with no established skincare benefits and potential sensitization concerns that makes it unsuitable for facial skincare applications.


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