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3-METHYLNON-2-ENENITRILE.

Avoid CAS 53153-66-5 / PERFUMING

A synthetic fragrance compound that delivers citrus-like scent profiles in cosmetic formulations. Despite its aromatic properties, this ingredient has been flagged by international safety bodies due to its significant potential to cause allergic skin reactions.

fragrance

Science

Functions exclusively as a fragrance agent providing citrus notes, but operates as a hapten by binding to skin proteins and triggering immune system responses that can result in contact dermatitis in susceptible individuals.


Research

High confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted
Red flag below
0.2%

Any presence above 0.2% concentration represents a significant safety concern due to documented dermal sensitization at this level


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Exhibits stability in standard cosmetic matrices but demonstrates high reactivity with skin proteins and susceptibility to oxidative degradation

Conflicts

  • Strong oxidizing agents
  • Strong alkaline compounds

Safety

CIR Status
Not reviewed
Max tested
0.2%
Pregnancy
Caution
Sensitization risk High

Banned by IFRA for fragrance applications, classified as Category 1 Skin Sensitizer and Category 2A Eye Irritant by European regulatory bodies


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

This ingredient presents unacceptable sensitization risks with no compensatory skincare benefits, warranting complete avoidance in modern formulations.


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