Science
Mechanism of Action
Functions as a selective agonist for the OR2AT4 olfactory receptor expressed in human keratinocytes, initiating calcium-dependent signaling cascades that activate MAPK/ERK and p38 pathways to enhance cellular proliferation and migration for improved re-epithelialization
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 Demonstrated activation of skin keratinocyte olfactory receptors leading to enhanced cell proliferation and migration for accelerated wound healing
Transparency
Dusting Analysis
Primary use as fragrance component with emerging skincare applications makes dusting unlikely
The Formula
Formulation
Stability
Exhibits exceptional stability in lipid-based formulations and emulsion systems with superior oxidation resistance compared to natural essential oils due to its secondary alcohol structure
Conflicts
- Strong oxidizing agents
- Strong acids
Safety
Safety Profile
Regulated under IFRA standards as fragrance ingredient with lower allergenicity profile than natural sandalwood oil, restricted to 1.2% maximum in leave-on products
Your Skin
Skin Compatibility
Our Assessment
Verdict
Innovative dual-function ingredient offering validated skin regeneration benefits through novel olfactory receptor activation with excellent safety profile.
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References
Sources