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Moumoujus

3-METHYL-4-(2,4,6-TRIMETHYL-3-CYCLOHEXENYL)-3-BUTEN-2-ONE.

Optional CAS 67801-29-0 / PERFUMING

A synthetic fragrance molecule from the methyl ionone family that delivers woody, floral, and violet-like scent characteristics to skincare formulations. While primarily serving as a perfuming agent, emerging research suggests potential skin barrier benefits through interaction with cutaneous olfactory receptors. This ingredient requires careful formulation due to its classification as a regulated fragrance allergen.

Summary

perfuming

Science

Mechanism of Action

Functions primarily through olfactory receptor interaction to provide fragrance properties, with emerging evidence suggesting possible modulation of keratinocyte proliferation and skin barrier repair via cutaneous olfactory receptors like OR2AT4, though fragrance remains its established commercial purpose.

Research

Clinical Evidence

Low confidence
Effective range 0.001–2%
Optimal

1%

Key findings

  1. 01 Accelerated epidermal barrier recovery by over 15% at day 7 post-tape stripping in alpha-ionone hydrogel formulations

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.001%
Red flag below
0.001%

Must be declared on labels above 0.001% in leave-on products due to fragrance allergen regulations, making dusting impractical for most commercial applications

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Demonstrates high stability in diverse cosmetic matrices but requires protection from light and elevated temperatures to prevent oxidative degradation into allergenic hydroperoxides

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk Moderate

Listed among 26 mandatory-disclosure fragrance allergens in EU regulations; sensitization possible at concentrations as low as 0.001% in previously sensitized individuals

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Effective fragrance ingredient with potential barrier benefits, but allergen status limits broader skincare applications.

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