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Moumoujus

3-HEXENAL.

Optional CAS 4440-65-7 / PERFUMING

A naturally-occurring Green Leaf Volatile that delivers the distinctive fresh-cut grass aroma to skincare formulations. This aldehyde compound functions primarily as a fragrance ingredient and scent-masking agent, though it requires careful formulation due to its inherent instability.

Summary

perfuming masking

Science

Mechanism of Action

Acts as an aromatic molecule that binds to olfactory receptors to provide fresh, herbaceous scent masking in topical applications, while potentially offering mild antimicrobial properties through its aldehyde structure.

Research

Clinical Evidence

Medium confidence
Effective range ≤0.5%
Optimal

0.5%

Key findings

  1. 01 Maximum recommended usage level established through RIFM safety assessments covering skin sensitization and systemic toxicity profiles

Transparency

Dusting Analysis

Not commonly dusted

Specialized fragrance ingredient with clear usage limitations rather than a commonly over-formulated active component

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Extremely unstable compound prone to oxidation and isomerization to trans-2-hexenal under ambient conditions; requires stabilization with solvents like triacetin or dipropylene glycol

Conflicts

  • strong oxidizing agents
  • strong bases
  • heat exposure
  • prolonged air exposure

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Moderate

Regulated under IFRA/RIFM standards; FDA GRAS-approved for flavoring applications; potential respiratory and ocular irritant at elevated concentrations

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Specialized fragrance ingredient with distinctive fresh scent profile but significant formulation challenges due to instability.

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