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3-GLYCERYL ASCORBATE.

Valuable CAS - / ANTIOXIDANT, HUMECTANT

A stabilized vitamin C derivative that combines L-ascorbic acid with glycerin for enhanced skin penetration and moisture retention. This dual-action compound delivers potent antioxidant benefits while providing superior hydration compared to pure vitamin C. Its stable molecular structure prevents oxidation and formula discoloration, making it ideal for transparent brightening formulations.

antioxidant skin brightening moisturizer/humectant anti-aging

Science

Functions as a prodrug that enzymatically releases pure vitamin C upon skin absorption. Inhibits tyrosinase activity to reduce melanin production for brightening effects, scavenges reactive oxygen species to prevent photoaging damage, and serves as a cofactor for prolyl hydroxylase to stimulate collagen synthesis. The glyceryl component simultaneously acts as a humectant, drawing moisture into the skin barrier.


Research

High confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 At 2-10% concentration: demonstrates melanin production inhibition and enhanced collagen synthesis through proline/lysine hydroxylation pathways
  2. 02 At 1-5% concentration: shows superior moisturizing performance versus L-ascorbic acid while maintaining equivalent antioxidant activity

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Effective concentrations begin at 1%, making sub-0.5% amounts insufficient for meaningful vitamin C delivery or hydration benefits


The Formula

Solubility
Water
Optimal pH 3 – 5
0 7 14

Stability

Heat-sensitive ingredient requiring water phase incorporation below 40°C to maintain potency. Demonstrates exceptional oxidative stability compared to L-ascorbic acid derivatives.

Synergies

  • Hyaluronic Acid
  • Niacinamide
  • Peptides

Conflicts

  • High electrolyte concentrations >2%
  • Sodium Lauryl Sulfate >30%
  • Strong electrophiles

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Recognized as safe within ascorbic acid derivative category with established use concentrations up to 10% in commercial formulations


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-researched vitamin C derivative that effectively combines antioxidant protection with hydration benefits across all skin types.


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