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Moumoujus

3-AMINOPROPANE SULFONIC ACID.

Insufficient Data CAS 3687-18-1 / SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

A multifunctional amino acid derivative that operates as both a gentle exfoliating agent and formulation enhancer. This compound facilitates natural skin cell turnover by breaking down the protein bonds that hold dead cells together, while simultaneously improving the solubility and delivery of other active ingredients in water-based formulations.

Summary

surfactant cleansing hydrotrope exfoliant

Science

Mechanism of Action

Functions as a glycosaminoglycan mimetic that targets corneodesmosomes—the protein structures binding dead skin cells in the stratum corneum. By promoting the degradation of these cellular adhesions, it accelerates natural desquamation and epidermal renewal. Additionally serves as a hydrotrope, enhancing ingredient penetration and formulation stability.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrated 39-65% increase in corneodesmosine degradation, supporting desquamation and cellular renewal
  2. 02 Research showed 30% reduction in protein aggregation, indicating potential anti-aging benefits

Transparency

Dusting Analysis

Not commonly dusted

Insufficient market data available for dusting analysis due to specialized nature of ingredient

The Formula

Formulation

Solubility
Water
Optimal pH 1 – 7.4
0 7 14

Stability

Highly water-soluble with excellent pH stability across biological range. Functions as buffering agent with predicted pKa of 1.06. Maintains stability in aqueous systems.

Synergies

  • Other water-soluble actives requiring enhanced penetration
  • Complex formulations requiring solubility enhancement

Conflicts

  • N-nitrosating agents
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

GHS classification indicates potential skin and eye irritation (H315, H319) in concentrated form. General alpha-amino acids are considered safe as used up to 18% concentration.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Promising dual-action ingredient with limited clinical validation requiring further research for definitive assessment.

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