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3,5-DIMETHYLCYCLOHEXYLMETHYL ACETATE.

Optional CAS 68213-86-5 / PERFUMING

A cyclohexyl ester compound that serves as a fragrance ingredient in cosmetic formulations, delivering fresh, minty, and herbal olfactory notes. Beyond its perfuming properties, this oil-soluble ester acts as a mild solvent that enhances the diffusion of complementary aromatic compounds throughout the formulation.

perfuming masking solvent

Science

Functions as an olfactory modifier through volatile aromatic compounds that provide masking and perfuming benefits, while its ester structure enables it to act as a blending agent that facilitates the uniform distribution of other fragrance molecules in oil-based systems.


Research

Medium confidence
Effective range 2.5–20%
Optimal

N/A

Key findings

  1. 01 HRIPT study at 20% concentration showed no skin sensitization reactions in 6202 μg/cm² application
  2. 02 Human patch testing at 2.5% concentration demonstrated absence of sensitization at 1938 μg/cm² dose

Transparency

Not commonly dusted

Primarily used as a fragrance component rather than an active ingredient, making dusting practices less relevant for this compound


The Formula

Solubility
Oil
Optimal pH 4 – 7.5
0 7 14

Stability

Demonstrates excellent stability in neutral to mildly acidic environments, particularly in body care and cleansing formulations. Susceptible to ester hydrolysis under highly alkaline conditions.

Synergies

  • Other fragrance compounds
  • Oil-based carriers

Conflicts

  • Strong oxidizing agents
  • Strongly aqueous bases
  • Strong aqueous acids

Safety

CIR Status
Not reviewed
Max tested
20%
Sensitization risk Low

Recognized as safe for flavor applications by FEMA (#4512) and included on IFRA transparency list. Evaluated by RIFM safety protocols with potential for increased irritancy when combined with other sensitizing agents.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient with demonstrated safety at concentrations up to 20%, suitable for most skin types except sensitive skin.


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