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3,5-DIMETHYL CYCLOHEXENECARBONITRILE.

Optional CAS 66848-40-6 / PERFUMING

A synthetic fragrance molecule with a distinctive tonka-like, coumarinic scent profile used primarily as a perfuming agent in cosmetic formulations. This nitrile compound contributes sensory properties to products but lacks direct therapeutic benefits for skin health.

perfuming

Science

Functions exclusively as an olfactory modifier, providing fragrance characteristics without any direct biological interaction with skin cells or therapeutic mechanisms of action on cutaneous tissues.


Research

Low confidence
Effective range ≤0.5%
Optimal

N/A


Transparency

Not commonly dusted

As a fragrance ingredient with no skincare benefits, inclusion appears legitimate when used for scenting purposes in appropriate concentrations.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Stable under neutral to mildly acidic/alkaline conditions; susceptible to hydrolysis at extreme pH levels converting to carboxylic acid or amide derivatives. LogP of 2.52 indicates poor water solubility at approximately 167 mg/L.

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong bases

Safety

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Moderate

Subject to IFRA fragrance standards with restricted usage levels due to potential sensitization concerns typical of nitrile compounds. Listed in EU CosIng database as approved perfuming agent.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A functional fragrance ingredient with no skincare benefits, appropriate for scenting formulations when used within safety guidelines.


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