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3,5-DIMETHOXYTOLUENE.

Optional CAS 4179-19-5 / PERFUMING

A naturally-derived aromatic compound found in Rosa chinensis that serves primarily as a fragrance ingredient in luxury skincare formulations. While its main function is olfactory, emerging research suggests this methoxylated phenol may offer secondary antioxidant benefits through free radical scavenging activity.

Fragrance Potential antioxidant

Science

Functions primarily through olfactory pathways to provide rose-like fragrance notes, while potentially offering mild antioxidant activity by neutralizing free radicals and reducing oxidative stress markers in skin tissue.


Research

Low confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 IFRA fragrance safety assessment demonstrating effective perfuming at 0.1-1.0% concentrations
  2. 02 In vitro antioxidant activity studies on related methoxylated phenolic compounds

Transparency

Not commonly dusted

Not typically used for active skin benefits claims, primarily serves fragrance function at regulated concentrations


The Formula

Solubility
Oil
Optimal pH 4.5 – 7.5
0 7 14

Stability

Exhibits excellent stability in anhydrous and lipophilic systems with limited water solubility of 7.6 g/L. Requires storage away from light and heat to prevent volatile loss and oxidative degradation.

Synergies

  • Rose essential oils
  • Other aromatic compounds
  • Oil-based carriers

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Not reviewed
Max tested
1%
Pregnancy
Safe
Sensitization risk Low

Regulated under IFRA guidelines rather than CIR review. Classified as GHS Category 2 irritant in pure form but safe at cosmetic use concentrations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient with potential but unproven antioxidant benefits, suitable for enhancing sensory experience in premium formulations.


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