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Moumoujus

2-TERT-BUTYLHYDROQUINONE METHYL ETHER.

Optional CAS 121-00-6 / PERFUMING

A synthetic phenolic antioxidant that protects cosmetic formulations from oxidative degradation by neutralizing free radicals. This oil-soluble compound acts as a chain-breaking antioxidant, primarily used to preserve the stability of lipid-based skincare products. Also known as a component of BHA (Butylated Hydroxyanisole), it prevents rancidity in oil-containing formulations.

Summary

antioxidant preservative perfuming

Science

Mechanism of Action

Donates hydrogen atoms from its hydroxyl group to peroxy radicals, interrupting the chain reaction of lipid peroxidation and preventing degradation of oil-based components in skincare formulations

Research

Clinical Evidence

Medium confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 Functions effectively as chain-breaking antioxidant at 0.1-1.0% concentration in cosmetic formulations
  2. 02 Patch testing at 2.0% concentration used clinically to identify contact allergy sensitivity

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.01%

As a preservative antioxidant, even trace amounts below 0.1% may indicate formula dusting rather than meaningful protection

The Formula

Formulation

Solubility
Oil
Optimal pH 3 – 7
0 7 14

Stability

Highly stable in neutral and acidic conditions but degrades rapidly above pH 9. Sensitive to air and light exposure, requiring opaque packaging and inert storage conditions.

Conflicts

  • Oxidizing agents
  • Strong bases
  • Nitrosating agents

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.5%
Sensitization risk Low

IARC Group 2B possible human carcinogen based on high-dose animal studies, but considered low risk at cosmetic-use concentrations. CIR and EU SCCS approve use up to 0.5%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A functional antioxidant preservative with regulatory approval but limited direct skin benefits and potential long-term safety considerations.

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