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2-SEC-BUTYLCYCLOHEXANONE.

Optional CAS 14765-30-1 / PERFUMING

A synthetic ketone primarily utilized as a fragrance and cooling agent, imparting a woody, minty aroma. It is incorporated into topical formulations to deliver a fresh, cooling sensation.

perfuming cooling agent

Science

This ingredient functions by potentially interacting with cold-sensing TRPM8 receptors, eliciting a subtle cooling effect akin to menthol. Its primary application in cosmetics is as an olfactive component or a fragrance masking agent.


Research

Medium confidence
Effective range N/A
Optimal

0.69%

Key findings

  1. 01 A human maximization test at 0.69% demonstrated no reactions indicative of skin sensitization or irritation.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 3 – 8
0 7 14

Stability

Exhibits good stability under normal storage conditions; avoid extreme heat to maintain integrity. Being a ketone, it is generally stable but should be kept from strong oxidizing agents.

Conflicts

  • strong acids
  • strong alkalis
  • oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

Thoroughly assessed by RIFM and the Expert Panel for Fragrance Safety (2024), deemed safe for its intended use. It is not genotoxic, photoirritating, or a skin sensitizer at typical use levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

An optional ingredient for formulations seeking a precise woody-minty fragrance and subtle cooling sensation, demonstrating a robust safety profile.


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