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2-NITRO-5-GLYCERYL METHYLANILINE.

Optional CAS 80062-31-3 / HAIR DYEING

A synthetic nitro dye compound primarily used in hair coloring formulations to impart yellow to yellow-orange hues. This direct-acting colorant penetrates hair shafts through physical affinity rather than chemical oxidation, making it suitable for both semi-permanent and oxidative hair treatments.

hair dyeing color depositing

Science

Functions as a direct nitro dye by diffusing into hair keratin structures due to its low molecular weight, binding through physical affinity without requiring chemical developers or oxidation reactions


Research

High confidence
Effective range 0.8–1%
Optimal

1%

Key findings

  1. 01 SCCS percutaneous absorption study at 0.9% showed minimal skin penetration (0.55% of applied dose over 24 hours)
  2. 02 SCCNFP toxicity assessment at 1.0% established NOAEL of 100 mg/kg bw/day in rat studies

Transparency

Not commonly dusted

Specialized hair dye ingredient with specific regulatory limits, not typically subject to concentration manipulation


The Formula

Solubility
Both
Optimal pH 2 – 11
0 7 14

Stability

Maintains stability for minimum 30 minutes under oxidative conditions and demonstrates long-term stability in acidic formulations. Light-sensitive requiring protected storage conditions.

Conflicts

  • nitrosating agents
  • strong oxidizing agents for extended periods

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

EU regulated under Annex III/218. Maximum 1.0% in non-oxidative formulations, 0.8% on-head concentration for oxidative products. Secondary amine structure creates nitrosation susceptibility.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

Specialized hair colorant with established safety profile but limited skincare applications beyond cosmetic hair treatments.


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