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2-METHYLPROPANOL.

Optional CAS 78-83-1 / PERFUMING

2-Methylpropanol is a branched-chain alcohol that serves dual purposes in skincare formulations as both a solvent and fragrance carrier. Also recognized by its alternative names isobutanol and isobutyl alcohol, this volatile compound helps dissolve active ingredients while contributing to product aesthetics. Its molecular structure allows it to function effectively across diverse formulation types, though its primary value lies in supporting rather than starring roles.

solvent fragrance

Science

Functions as a multifunctional solvent that dissolves both hydrophilic and lipophilic ingredients, facilitating uniform distribution throughout formulations. Additionally acts as a fragrance carrier, helping to stabilize and deliver aromatic compounds. May provide secondary penetration enhancement by temporarily modifying stratum corneum lipid organization, though this effect is incidental to its primary solvent function.


Research

Medium confidence
Effective range ≤50%
Optimal

N/A

Key findings

  1. 01 Demonstrated minimal skin irritation in controlled rabbit ear assays with primary irritation index of 0.4 out of 8, classified as non-irritating to slightly irritating

Transparency

Not commonly dusted

As a functional solvent rather than an active ingredient, 2-methylpropanol is not typically subject to dusting practices in cosmetic formulations


The Formula

Solubility
Both
Optimal pH 4 – 9
0 7 14

Stability

Exhibits excellent stability across broad pH ranges due to its simple alcohol structure, but requires careful handling due to high volatility and potential for evaporation loss

Conflicts

  • Strong oxidizing agents
  • Aluminum at elevated temperatures
  • Acid chlorides

Safety

CIR Status
Safe as used
Max tested
100%
Sensitization risk Low

FDA-approved as indirect food additive solvent with established safety profile, though concentrated forms present flammability risks and potential for serious eye irritation upon direct contact


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A competent functional ingredient for specific formulation needs, though not essential for most skincare applications.


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