Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

2-METHYLPENT-3-ENOIC ACID.

Questionable CAS 37674-63-8 / PERFUMING

A methyl-branched unsaturated fatty acid primarily employed as a fragrance component in skincare formulations, delivering fruity, green, and tropical aromatic notes. While structurally classified as a fatty acid, it functions exclusively as a volatile organic compound for sensory enhancement rather than providing any documented skin-corrective benefits.

perfuming

Science

Acts as a volatile aromatic compound that interacts with olfactory receptors to provide sensory enhancement in formulations. Despite belonging to the fatty acid class, no evidence supports physiological skin conditioning, antioxidant activity, or therapeutic effects on skin barrier function.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Limited use as fragrance component makes dusting unlikely, though lack of skin benefits may lead to inclusion without meaningful contribution to product efficacy.


The Formula

Solubility
Both
Optimal pH 4.5 – 5.5
0 7 14

Stability

Exhibits limited water solubility (8-19 g/L) with high solubility in alcohols and fixed oils. Most stable in undissociated form at acidic pH due to pKa of 4.88, typically incorporated within oil or alcohol phases for fragrance applications.

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Reducing agents

Safety

CIR Status
Not reviewed
Max tested
0.1%
Sensitization risk High

FEMA GRAS status for dietary use (FEMA #3464) and JECFA evaluation showing no safety concerns at intake levels. However, concentrated form classified as GHS H314 (severe skin burns and eye damage) and Skin Corrosive 1B, necessitating restriction to very low concentrations below 0.1% for topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Questionable

A fragrance ingredient with high irritancy potential and no documented skin benefits, warranting careful concentration control and avoidance in sensitive skin formulations.


Related

Finding similar ingredients…