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2-METHYLDODECANAL.

Optional CAS 37596-36-4 / PERFUMING

A synthetic aldehyde compound primarily utilized as a fragrance component in cosmetic formulations, delivering fresh citrusy and coniferous scent notes. This oil-soluble ingredient serves exclusively as a perfuming agent with no established dermatological benefits beyond sensory enhancement.

perfuming

Science

Functions solely as an olfactory modifier by interacting with scent receptors to provide fragrance characteristics, with no direct physiological activity on skin cells or tissue repair mechanisms.


Research

Medium confidence
Effective range 0.05–0.5%
Optimal

0.1%

Key findings

  1. 01 RIFM safety evaluation demonstrated skin sensitization potential in a minority of subjects at elevated concentrations, with acceptable tolerability at standard usage levels

Transparency

Not commonly dusted

As a fragrance ingredient with known sensitization potential, this compound is typically used at controlled concentrations rather than being dusted for marketing purposes.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Susceptible to oxidative degradation when exposed to air and light, converting to corresponding carboxylic acid; requires storage in sealed, light-protective containers

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Primary amines

Safety

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Moderate

Regulated under IFRA guidelines as a recognized skin sensitizer with concentration limits varying by product category


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A standard fragrance component with moderate sensitization risk that provides scent enhancement but no skincare benefits.


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