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2-METHYLBUTYRIC ACID.

Optional CAS 116-53-0 / PERFUMING

A short-chain fatty acid derivative primarily employed as a fragrance component in cosmetic formulations, offering subtle fruity and creamy scent notes. While structurally related to skincare acids, this ingredient functions exclusively as a perfuming agent rather than an active treatment component. Despite its acid classification, it lacks the exfoliating or skin-renewing properties associated with established skincare acids.

perfuming

Science

Functions primarily as an olfactory enhancer, contributing fruity and creamy fragrance notes to cosmetic products. As a short-chain fatty acid, it may theoretically support the skin's natural acid mantle maintenance, though this occurs only as a secondary effect at the minimal concentrations used for fragrance purposes.


Research

Low confidence
Effective range ≤0.07%
Optimal

N/A

Key findings

  1. 01 Demonstrated no significant tumorigenicity effects in skin application studies
  2. 02 Human maximization testing revealed no skin sensitization reactions

Transparency

Not commonly dusted

Not typically used as a marketing-driven active ingredient; appears in ingredient lists solely for fragrance purposes at minimal effective concentrations


The Formula

Solubility
Both
Optimal pH 3 – 5
0 7 14

Stability

Maintains stability in acidic environments but degrades under alkaline conditions above pH 7.0, potentially forming butyric acid with undesirable rancid odor characteristics

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Reactive metals

Safety

CIR Status
Safe as used
Max tested
0.07%
Pregnancy
Safe
Sensitization risk Low

Concentration limits vary by product type: 0.02% maximum in deodorants, up to 0.07% in lip products. Concentrated form requires handling precautions due to corrosive classification.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A safe but functionally limited fragrance ingredient with no demonstrated skincare benefits beyond scent enhancement.


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References