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2-METHYL-5-METHYLVINYL-CYCLOHEXANOL.

Optional CAS 38049-26-2 / PERFUMING

A monoterpenoid alcohol that serves dual purposes as a fragrance component and penetration enhancer in skincare formulations. This terpene-based compound modifies skin barrier permeability to improve the delivery of active ingredients while providing subtle woody-floral notes.

Penetration enhancer Fragrance component Delivery system modifier

Science

Functions by disrupting the organized lipid structure of the stratum corneum, creating temporary channels that allow enhanced penetration of accompanying active ingredients into deeper skin layers. At higher concentrations, may promote localized microcirculation through mild inflammatory stimulation.


Research

Medium confidence
Effective range 0.1–4%
Optimal

1%

Key findings

  1. 01 No irritation or sensitization observed in human patch testing

Transparency

Not commonly dusted

Primarily used as a functional fragrance and penetration enhancer rather than a marketing-driven active ingredient


The Formula

Solubility
Oil
Optimal pH 4 – 9
0 7 14

Stability

Demonstrates excellent stability across alkaline conditions with high resistance to oxidative degradation. Maintains structural integrity in detergent systems and high-pH environments.

Synergies

  • Other active ingredients requiring enhanced penetration

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Not reviewed
Max tested
6%
Sensitization risk Low

Listed in IFRA Transparency List and EU CosIng database. Industry guidelines suggest 6% maximum in fragrance concentrates. GHS classification indicates potential skin irritation at high purity levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A specialized functional ingredient best suited for formulations requiring enhanced active delivery rather than standalone skincare benefits.


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