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Moumoujus

2-METHYL-4-(2,2,3-TRIMETHYL-3-CYCLOPENTENYL)-2-BUTEN-1-OL.

Valuable CAS 28219-60-5 / PERFUMING

A synthetic sandalwood-scented compound that uniquely activates olfactory receptors in skin cells to accelerate cellular repair processes. This innovative ingredient demonstrates remarkable dual functionality, serving both as an elegant fragrance component and a scientifically-backed skin regeneration enhancer through its targeted receptor activation.

Summary

fragrance skin regenerating soothing anti-aging

Science

Mechanism of Action

Operates as a selective agonist for the OR2AT4 olfactory receptor present in keratinocytes, triggering calcium influx that activates cAMP-dependent pathways and phosphorylates key signaling proteins (Erk1/2, p38 MAPK). This cascade stimulates cellular proliferation, enhances migration for wound repair, and activates autophagy pathways that combat oxidative stress-induced aging.

Research

Clinical Evidence

High confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 Human keratinocyte studies showing 32% increase in cell proliferation and 18% enhancement in migration at 0.1-1.0% concentrations
  2. 02 Reconstructed human epidermis trials at 1.0% demonstrating significant anti-senescence effects and restoration of Ki-67 proliferation markers

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Given its dual role as fragrance and active ingredient, concentrations below 0.05% likely provide only minimal sensory benefit without meaningful skin regeneration effects

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Demonstrates excellent oxidative stability due to substituted cyclopentyl structure. Maintains integrity in emulsions and alcohol-based systems but degrades in highly acidic conditions below pH 3.5.

Synergies

  • Emulsion systems
  • Alcohol-based formulations
  • Body lotions and soaps

Conflicts

  • Strong oxidizing agents
  • Hypochlorite bleach
  • Highly acidic environments (pH < 3.5)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1.2%
Sensitization risk Low

IFRA and SCCS guidelines suggest 1.2% maximum in leave-on products to prevent sensitization. Pure compound classified as skin irritant (GHS H315), but formulated products show low irritancy potential.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A scientifically innovative ingredient that uniquely combines sensory appeal with proven cellular regeneration benefits through novel receptor-mediated mechanisms.

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