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2-METHYL-3-OXOPROPOXY-PYRAN-4-ONE.

Optional CAS 68555-63-5 / PERFUMING

A maltol-derived compound that serves multiple functions in skincare formulations, combining fragrance enhancement with antioxidant protection. This versatile ingredient provides free radical scavenging capabilities while delivering a subtle cooling sensation through TRPM8 receptor modulation.

fragrance antioxidant skin conditioning

Science

Functions primarily through free radical neutralization and lipid peroxidation inhibition, protecting skin from oxidative stress. Additionally modulates TRPM8 receptors to create mild cooling effects while providing skin conditioning benefits through its propionate ester structure.


Research

Medium confidence
Effective range 0.1–2.5%
Optimal

2.5%

Key findings

  1. 01 RIFM Fragrance Material Safety Assessment demonstrated non-sensitizing properties at 2.5% concentration in finished products with documented antioxidant benefits

Transparency

Not commonly dusted

Primarily used as a functional fragrance component rather than an active ingredient, making dusting practices less relevant


The Formula

Solubility
Oil
Optimal pH 4.5 – 6.5
0 7 14

Stability

Demonstrates excellent stability under standard storage conditions with enhanced solubility in alcohols and organic solvents compared to water

Conflicts

  • Nitrosating agents
  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
2.5%
Sensitization risk Low

FDA-approved synthetic flavoring substance with RIFM assessment confirming absence of photoirritation and photoallergy concerns at declared use levels


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A multifunctional ingredient offering modest antioxidant benefits with excellent safety profile, though primarily valued for fragrance enhancement rather than significant skincare efficacy.


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