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2-METHYL-3-BUTEN-2-OL.

Optional CAS 115-18-4 / PERFUMING

A tertiary terpene alcohol derived from hop bitter acids that serves as a fragrance component and solvent in cosmetic formulations. While primarily used for its aromatic properties, emerging research suggests potential anti-inflammatory benefits through modulation of neutrophil activation.

perfuming solvent

Science

Functions primarily as a fragrance agent and penetration enhancer due to its small molecular size and volatility. May provide anti-inflammatory effects by inhibiting neutrophil activation and chemotaxis, though this mechanism requires further validation in topical applications.


Research

Low confidence
Effective range ≤0.05%
Optimal

0.05%

Key findings

  1. 01 Demonstrated as safe maximum usage level with no skin irritation at consumer-relevant concentrations

Transparency

Not commonly dusted

Limited use as a functional skincare ingredient; primarily serves fragrance and solvent roles rather than active benefits


The Formula

Solubility
Both
Optimal pH 9 – 10
0 7 14

Stability

Highly volatile compound requiring careful handling; exhibits optimal stability under alkaline conditions. More oxidation-resistant than primary alcohols due to tertiary structure.

Conflicts

  • Strong oxidizing agents
  • Acid anhydrides
  • Acid chlorides
  • Alkali metals

Safety

CIR Status
Not reviewed
Max tested
0.05%
Sensitization risk Low

Evaluated by RIFM and IFRA for fragrance safety. Pure form classified as skin/eye irritant but non-irritating at typical cosmetic concentrations below 0.05%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A safe fragrance ingredient with limited skincare benefits beyond sensory enhancement and potential penetration enhancement properties.


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