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2-METHYL-2-OCTANOL.

Questionable CAS 628-44-4 / PERFUMING

A tertiary fatty alcohol that serves dual purposes as a fragrance component and mild emollient in skincare formulations. While it can help reduce transepidermal water loss through barrier formation, its primary role remains as an aromatic agent contributing to product scent profiles.

perfuming emollient

Science

Functions primarily through fragrance delivery while providing secondary emollient benefits by forming a light hydrophobic film on the skin surface that helps minimize moisture loss


Research

Medium confidence
Effective range ≤1%
Optimal

N/A

Key findings

  1. 01 Patch testing in eczema patients revealed sensitization rates of 0.83-1.67% at 1-2% concentrations, establishing safety thresholds below 1%

Transparency

Not commonly dusted
Red flag below
1%

Not typically used for marketing inflation, but concentrations at or above 1% present sensitization risks based on patch test data


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Demonstrates excellent chemical stability as a tertiary alcohol under standard storage conditions, with low water solubility of approximately 495 mg/L

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

GHS classifies as Category 2 skin irritant and Category 2A eye irritant; patch testing indicates active sensitization potential at 1% and above


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Questionable

While functional as a fragrance agent with mild emollient properties, the moderate sensitization risk and irritancy profile make it less suitable for precision skincare applications.


Related

Finding similar ingredients…


References