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2-HEXYLIDENECYCLOHEXAN-1-ONE.

Optional CAS 16429-07-5 / PERFUMING

A fragrance compound that adds woody and floral scent notes to cosmetic formulations. As an alpha,beta-unsaturated carbonyl compound, it carries moderate sensitization potential due to its ability to bind with skin proteins.

perfuming

Science

Functions purely as a fragrance agent, providing olfactory enhancement through volatile aromatic compounds. Its chemical reactivity as an unsaturated ketone allows it to act as a potential hapten, forming protein conjugates that may trigger allergic contact dermatitis in susceptible individuals.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted
Red flag below
0.086%

IFRA regulations cap usage at 0.086% in hydroalcoholic products and 0.023% in lip products due to sensitization concerns


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Maintains stability under standard cosmetic storage conditions as an unsaturated ketone structure

Conflicts

  • Strong oxidizing agents
  • Strong bases

Safety

CIR Status
Not reviewed
Max tested
0.086%
Sensitization risk Moderate

IFRA 51st Amendment regulated with NESIL established at 300 μg/cm². Human patch testing at 0.3% showed no sensitization, while 0.5% concentrations of similar compounds induced reactions in 8% of test subjects.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A regulated fragrance ingredient suitable for non-sensitive skin types when used within IFRA concentration limits.


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