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Moumoujus

2-ETHYLBUTYRIC ACID.

Questionable CAS 88-09-5 / PERFUMING

A branched-chain fatty acid primarily employed as a fragrance component and formulation aid in cosmetic products. While possessing a characteristically pungent odor that requires careful formulation management, it serves functional roles as a pH modifier and micellar system stabilizer. Its primary value lies in supporting product sensory profiles and enhancing delivery system stability rather than providing direct skin benefits.

Summary

Perfuming Masking pH adjusting Formulation aid

Science

Mechanism of Action

Functions predominantly through its carboxylic acid group (pKa ~4.75) to adjust product pH and modify formulation characteristics. In advanced delivery systems, it acts as a lipophilic structural modifier that stabilizes nonionic surfactant micelles, potentially improving the delivery of fat-soluble actives by altering the hydrophobic micellar core.

Research

Clinical Evidence

Low confidence
Effective range ≤10%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Not commonly used for marketing claims as it functions primarily as a formulation aid rather than an active ingredient

The Formula

Formulation

Solubility
Both
Optimal pH 3 – 5
0 7 14

Stability

Limited water solubility at approximately 18g/L but readily dissolves in ethanol and oils. Maintains highest stability in acidic environments where it remains in neutral form.

Synergies

  • Tween 80
  • Nonionic surfactants

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Isocyanates
  • Amines

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Classified as GHS Category 3 for dermal toxicity and serious eye irritant. RIFM and IFRA have evaluated for fragrance use. FDA-approved as flavoring agent (FEMA 2429).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

A functional ingredient with limited skin benefits and notable irritation potential, best reserved for specialized formulation applications.

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