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Moumoujus

2-ETHYL-3,5-DIMETHYLPYRAZINE.

Optional CAS 13925-07-0 / PERFUMING

A pyrazine derivative primarily utilized as a fragrance component in cosmetic formulations, delivering gourmand and nutty aromatic notes. While recognized as safe for food flavoring applications, its topical skincare benefits remain largely unestablished through clinical research. The compound demonstrates lipoxygenase inhibitory activity in laboratory studies, suggesting potential anti-inflammatory properties, though this has not been validated for dermatological applications.

Summary

Perfuming

Science

Mechanism of Action

Functions predominantly as a fragrance agent with limited established skin-specific mechanisms. Laboratory studies indicate inhibition of lipoxygenase enzymes involved in inflammatory pathways, though clinical relevance for topical application remains unproven. No documented effects on collagen synthesis, melanin production, or other established skincare pathways.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Lipoxygenase inhibition demonstrated in vitro (Biosynth studies)
  2. 02 Mammalian cell growth inhibition observed in laboratory cultures

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as fragrance component at low concentrations, not typically subject to dusting practices in skincare formulations

The Formula

Formulation

Solubility
Both
Optimal pH 1 – 9
0 7 14

Stability

Exhibits exceptional thermal stability and maintains integrity across wide pH range (1.0-9.0). Low volatility profile makes it suitable for heat-processed formulations. Demonstrates consistent performance under varying temperature conditions.

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

FEMA GRAS status for food use (FEMA #3149). GHS classification indicates Category 2 skin irritant and Category 2A eye irritant for pure substance. NOAEL established at 12.5-18 mg/kg/day for oral consumption.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A specialized fragrance ingredient with unproven skincare benefits and moderate irritation potential, best reserved for scented formulations where aromatic profile is the primary objective.

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